研究队伍
人才库

韩伟

职称:研究员

专业:生物物理学

电话:0551-65595100

单位:医学物理与技术中心

E-mail:hanw@hfcas.ac.cn

地址:安徽省合肥市蜀山湖路350号医学物理与技术中心 邮编:230031

简历

博士生导师,医学物理中心辐射生物医学研究室主任;中国生物物理学会辐射与环境专业青年委员会副主任委员 

2006年6月毕业于中国科学院等离子体物理研究所,获博士学位 

2007年5月—2008年5月:哈佛大学医学院麻省总医院放射肿瘤系(Department of Radiation Oncology, Massachusetts General Hospital/Harvard Medical School)博士后研究员(Post-Doctoral Research Fellow); 

2006年9月—2007年4月:香港城市大学物理与材料科学系核辐射研究所 (Nuclear Radiation Unit, Department of Physics and Material Science, City University of Hong Kong)研究员(Research Fellow); 

2008年7月—2010年11月:香港城市大学物理与材料科学系核辐射研究所 (Nuclear Radiation Unit, Department of Physics and Material Science, City University of Hong Kong)高级研究副职 (Senior Research Associate) ;   

2010年11月—至今:中国科学院合肥物质科学研究院医学物理与技术中心,创新岗位研究员。  

研究领域 荣誉 学术论文 专利

电离辐射引发生物体遗传损伤效应、辐射引发的生物信号传递、放疗中的生物防护 

1.Jie Ma, Hao Zhang, Cheng Cheng, Jie Shen, Lingzhi Bao, Wei Han*. Contribution of hydrogen peroxide to non-thermal atmospheric pressure plasma induced A549 lung cancer cell damage, Plasma Processes and Polymers, 2016, DOI 10.1002/ppap.201600162.

2.Wenqing Wu, Lili Nie, K. N. Yu, Lijun Wu, Peizhong Kong, Lingzhi Bao, Guodong Chen, Haoran Yang and Wei Han*. Low Concentration of Exogenous Carbon Monoxide Modulates Radiation-Induced Bystander Effect in Mammalian Cell Cluster Model, International Journal of Molecular Science, 17, 2051, 2016.

3.Lingzhi Bao, Jie Ma, Guodong Chen, Jue Hou, Tom K. Hei, K.N. Yu, Wei Han*.Role of heme oxygenase-1 in low dose radioadaptive response, Redox Biology, 8, 333-340, 2016.

4.Wei Li, K.N. Yu, Lingzhi Bao, Jie Shen, Cheng Cheng, Wei Han*. Non-thermal plasma inhibits migration and invasion of human cervical cancer HeLa cells. Scientific Reports, 6, 19720, 2016.

5.Hongzhi Wang, K.N. Yu, Jue Hou, Qian Liu, Wei Han*. Radiation-induced bystander effect: Early process and rapid assessment, Cancer Letters, 356(1): 137-144, 2015.  (邀请综述)

6.Jue Hou, Jie Ma, K. N. Yu, Wei Li, Cheng Cheng, Lingzhi Bao, Wei Han*,Non-thermal plasma treatment altered gene expression profiling in non-small-cell lung cancer A549 cells, BMC Genomics, 16:435, 2015.

7.Jue Hou, Fan Wang, Peizhong Kong, K.N. Yu, Hongzhi Wang, Wei Han*, Gene profiling characteristics of radioadaptive response in AG01522 normal human fibroblasts. PLoS ONE 10, e0123316. doi:10.1371/journal.pone.0123316, 2015.

8.Liping Tong, K.N. Yu, Lingzhi Bao, Wenqing Wu, Hongzhi Wang, Wei Han*. Low concentration of exogenous carbon monoxide protects mammalian cells against proliferation induced by radiation-induced bystander effect, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 759(1): 9-15, 2014.

9.Wei Han, K.N. Yu, Lijun Wu, Yican Wu and Hongzhi Wang, Mechanism of protection of bystander cells by exogenous carbon monoxide: impaired response to damage signal of radiation-induced bystander effect, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2011, 709-710, 1-6.

10.Wei Han, Lijun Wu, Shaopeng Chen and K.N. Yu, Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed co-culture system after alpha-particle irradiation, Carcinogenesis, 2010, 31, 275-280.

11.Wei Han, Shaopeng Chen, K.N. Yu and Lijun Wu, Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after alpha-particle irradiation, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2010, 684, 81-89.

12.Wei Han, Lijun Wu, Shaopeng Chen, Linzhi Bao, Leilei Zhang, Erkang Jiang, Ye Zhao, An Xu, Tom K. Hei and Zengliang Yu, Constitutive nitric oxide acting as a possible intercellular signaling molecule in the initiation of radiation-induced DNA double strand breaks in non-irradiated bystander cells, Oncogene, 2007, 26, 2330-2339.

13.Wei Han, Lijun Wu , Burong Hu, Leilei Zhang, Shaopeng Chen, Lingzhi Bao, An Xu and Zengliang Yu, The early and initiation process of radiation-induced bystander effects involving in the induction of DNA double strand breaks in non-irradiated cultures, British Journal of Radiology, 2007, 80, S7-S12. (邀请文章)

14.Wei Han, Lingyan Zhu, Erkang Jiang, Jun Wang, Shaopeng Chen, Linzhi Bao, Ye Zhao, An Xu, Zengliang Yu, Lijun Wu, Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007, 624, 124-131.

15.Burong Hu#, Wei Han#, Lijun Wu, Huiyun Feng, Xuelan Liu, Leilei Zhang, An Xu, Tom K. Hei and Zengliang Yu, In situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low dose α-particle irradiation, Radiation Research, 2005, 164,286-291. (#:共同第一作者)

  

Book Chapters:

16.Wei Han, Peter K.N. Yu, Low Dose Radiation, DNA Double Strand Break and Mutation, Chapter 7 in Mutations: Types, Harmful Mutations and Beneficial Mutations, Nova Science Publishers, Inc. New York. 2010.

17.Wei Han, Peter K.N. Yu, Response of cells to ionizing radiation, Chapter 6 in Advances in Biomedical Science and Engineering, edited by S C Tjong, Bentham Science Publishes Ltd. Illinois. 204-262, 2009.